POU2F2

Across TCGA patient cohorts, POU2F2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POU2F2-associated genes across cancer lineages are IL2RB, SAMSN1, and CXCL13. Each is linked with POU2F2 in more than 6 cancer types. Because this analysis shows association rather than direction, both POU2F2-to-partner and partner-to-POU2F2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU2F2 versus IL2RB in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU2F2→partner) and Y-score (partner→POU2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL2RB →	+1.387	+0.975	<.001	<.001	3	7
UCEC	SAMSN1 →	+1.299	+1.069	<.001	<.001	3	7
PDAC	CXCL13 →	+2.881	+0.828	<.001	<.001	3	7
HNSC	CD7 →	+1.436	+1.140	<.001	<.001	3	7
PDAC	CD19 →	+1.376	+0.477	<.001	.001	3	7
UCEC	CD28 →	+0.868	+0.869	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,872 associations by consensus.

POU2F2 vs IL2RB — BRCA

Explore this scatter interactively →