POU2F2

Across TCGA cell cohorts, POU2F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,199 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POU2F2-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Regulation of intracellular protein transport, and Protein depolymerization. Each is linked with POU2F2 in more than 11 cancer types. Because this analysis shows association rather than direction, both POU2F2-to-partner and partner-to-POU2F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to mitochondrion grouped by POU2F2-low versus POU2F2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU2F2→partner) and Y-score (partner→POU2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein localization to mitochondrion →	+0.137	+1.540	<.001	<.001	3	12
PANCREAS	Regulation of intracellular protein transport →	+0.064	+0.804	.004	.007	3	11
BREAST	Protein depolymerization →	+0.093	+0.505	<.001	.001	3	10
STOMACH	Primary alcohol metabolic process →	-0.095	-1.523	<.001	<.001	3	10
STOMACH	Cellular response to toxic substance →	-0.128	-1.894	<.001	<.001	3	9
LIVER	Negative regulation of small GTPase mediated signal transduction →	+0.109	+1.377	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,199 associations by consensus.

Regulation of protein localization to mitochondrion by POU2F2 expression — SOFT_TISSUE

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