POU2AF1

Across TCGA patient cohorts, POU2AF1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,989 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POU2AF1-associated genes across cancer lineages are SLA2, PPP1R16B, and PIM2. Each is linked with POU2AF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both POU2AF1-to-partner and partner-to-POU2AF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU2AF1 versus SLA2 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU2AF1→partner) and Y-score (partner→POU2AF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLA2 →	+1.259	+0.810	<.001	<.001	3	4
HNSC	PPP1R16B →	+1.085	+0.651	<.001	<.001	3	4
HNSC	PIM2 →	+1.524	+0.779	<.001	<.001	3	4
HNSC	CD79A →	+3.707	+1.119	<.001	<.001	3	4
HNSC	P2RX1 →	+1.118	+0.777	<.001	<.001	3	4
LSCC	IL26 →	+0.827	+0.686	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,989 associations by consensus.

POU2AF1 vs SLA2 — BRCA

Explore this scatter interactively →