Across TCGA cell cohorts, POTEM RNA expression is significantly associated with the go_rna of many other GO terms, with 233 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POTEM-associated GO terms across cancer lineages are Regulation of potassium ion import, Peptidyl-lysine monomethylation, and Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with POTEM in more than 2 cancer types. Because this analysis shows association rather than direction, both POTEM-to-partner and partner-to-POTEM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEM→partner) and Y-score (partner→POTEM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of potassium ion import →	-0.215	-0.186	.002	.004	3	3
LIVER	Peptidyl-lysine monomethylation →	+0.098	+0.220	.001	.003	3	2
CNS	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.071	+0.090	<.001	.009	3	2
CNS	Positive regulation of telomere maintenance via telomere lengthening →	+0.044	+0.090	.006	.009	3	2
CNS	Central nervous system neuron differentiation →	-0.045	-0.132	<.001	.009	3	2
LUNG_NSCLC_LUAD	IMP salvage →	+0.112	+0.133	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

Exploration

POTEM survival (RNA) · tumor vs normal (RNA) · all POTEM data types