Across TCGA pan-cancer cohorts, POTEJ RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of POTEJ’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where POTEJ RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POTEJ is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, HNSC, and PRAD are the cancer types where POTEJ tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POTEJ RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.127	.008	6	view →
HNSC	All	II,III,IV	+0.029	.001	4	view →
PRAD	All	All	+0.223	.041	2	view →
THCA	All	All	−0.012	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: POTEJ RNA expression & survival · all POTEJ data types