Across TCGA patient cohorts, POTEI protein abundance is significantly associated with the RNA expression of many other genes, with 9,560 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POTEI-associated genes across cancer lineages are ZCCHC24, PODN, and TMEM119. Each is linked with POTEI in more than 6 cancer types. Because this analysis shows association rather than direction, both POTEI-to-partner and partner-to-POTEI results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEI→partner) and Y-score (partner→POTEI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZCCHC24 →	+0.833	+0.461	<.001	<.001	3	7
OV	PODN →	+0.934	+0.340	.001	<.001	3	7
CCRCC	TMEM119 →	+1.169	+0.285	<.001	<.001	3	7
LUAD	ITGBL1 →	+1.092	+0.236	<.001	<.001	3	7
COAD	COMP →	+2.050	+0.722	<.001	<.001	3	6
OV	SFRP4 →	+1.830	+0.394	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,560 associations by consensus.

Exploration

POTEI survival (RNA) · tumor vs normal (RNA) · all POTEI data types