POTEH-AS1

Across TCGA pan-cancer cohorts, POTEH-AS1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated POTEH-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher POTEH-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated POTEH-AS1 expression acts as an unfavorable survival marker, although some lineages such as PRAD show a favorable association.

KIRP, LUAD, and STAD are the cancer types where POTEH-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	II,III,IV	0.138	0.703	<.001	75	view →
LUAD	OS	Tertile	II,III,IV	0.150	0.709	.001	36	view →
STAD	OS	Tertile	III,IV	0.163	0.529	.003	27	view →
LUSC	DFS	Tertile	All	0.243	0.717	.001	27	view →
SKCM	DFS	Tertile	III,IV	0.161	0.509	.041	18	view →
TGCT	DFS	Tertile	All	0.099	0.801	.011	18	view →
KIRC	DFS	Tertile	All	0.381	0.636	.021	18	view →
OV	OS	Tertile	All	0.746	0.853	.011	18	view →
PRAD	DFS	Quartile	All	0.890	0.701	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

POTEH-AS1–KIRP (DFS)

Open the KIRP breakdown →