Across TCGA pan-cancer cohorts, POTEG Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated POTEG data layer compared with 24 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher POTEG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POTEG expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

SCLC, STAD, and LUAD are the cancer types where POTEG Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	36	view →
STAD	OS	Median	All	0.184	0.730	.001	33	view →
LUAD	OS	Median	All	0.211	0.697	.005	6	view →
SKCM	DFS	Median	II,III,IV	0.866	0.217	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: POTEG tumor-vs-normal RNA expression · all POTEG data types