Across TCGA patient cohorts, POTEF protein abundance is significantly associated with the RNA expression of many other genes, with 5,915 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POTEF-associated genes across cancer lineages are SRPX, MEOX2, and ACTA2. Each is linked with POTEF in more than 6 cancer types. Because this analysis shows association rather than direction, both POTEF-to-partner and partner-to-POTEF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEF→partner) and Y-score (partner→POTEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRPX →	+1.134	+0.524	<.001	.001	3	7
OV	MEOX2 →	+1.210	+1.044	<.001	<.001	3	6
OV	ACTA2 →	+1.371	+0.816	<.001	<.001	3	6
OV	CNRIP1 →	+0.649	+0.640	<.001	<.001	3	6
HNSC	RHOJ →	+0.732	+0.729	<.001	<.001	3	6
HNSC	ABCA6 →	+0.937	+0.608	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,915 associations by consensus.

Exploration

POTEF survival (RNA) · tumor vs normal (RNA) · all POTEF data types