POTED

Across TCGA patient cohorts, POTED mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POTED-associated genes across cancer lineages are LINC00709, MIR6803, and ARPP19P2. Each is linked with POTED in more than 1 cancer types. Because this analysis shows association rather than direction, both POTED-to-partner and partner-to-POTED results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00709 grouped by POTED-low versus POTED-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTED→partner) and Y-score (partner→POTED) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC00709 →	+0.098	+5.142	<.001	.002	3	2
UCEC	MIR6803 →	+0.555	+6.893	<.001	<.001	3	2
UCEC	ARPP19P2 →	+0.452	+4.354	<.001	.002	3	2
UCEC	RFKP1 →	+0.361	+6.242	<.001	<.001	3	2
LUSC	RN7SKP144 →	+0.116	+3.517	.001	.006	3	2
SKCM	ZFY-AS1 →	+0.293	+2.833	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

LINC00709 by POTED expression — COAD

Explore this box plot interactively →