POTED

Across TCGA patient cohorts, POTED mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. OV shows the largest number of these associations.

The most reproducible POTED-associated genes across cancer lineages are CD4+ naive T-cells and Neutrophils. Each is linked with POTED in more than 1 cancer types. Because this analysis shows association rather than direction, both POTED-to-partner and partner-to-POTED results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ naive T-cells grouped by POTED-low versus POTED-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTED→partner) and Y-score (partner→POTED) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD4+ naive T-cells →	+0.014	+6.197	<.001	.026	3	1
UCEC	Neutrophils →	+0.028	+2.751	<.001	.044	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ naive T-cells by POTED expression — OV

Explore this box plot interactively →