POTED

Across TCGA cell cohorts, POTED RNA expression is significantly associated with the mutation status of many other genes, with 72 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POTED-associated genes across cancer lineages are SUPT5H, FER1L6, and ARHGAP31. Each is linked with POTED in more than 1 cancer types. Because this analysis shows association rather than direction, both POTED-to-partner and partner-to-POTED results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUPT5H grouped by POTED-low versus POTED-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTED→partner) and Y-score (partner→POTED) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SUPT5H →	+3.169	+0.019	.005	<.001	3	2
BLOOD_Lymphoma	FER1L6 →	+3.452	+0.603	.004	<.001	3	2
BLOOD_Myeloma	ARHGAP31 →	+3.716	+0.276	.005	<.001	3	1
CNS	TDRD5 →	+4.263	+0.363	<.001	<.001	3	1
OVARY	AKAP10 →	+5.196	+0.012	.005	<.001	3	1
OVARY	ELN →	+5.196	+0.019	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

SUPT5H by POTED expression — LUNG_SCLC

Explore this box plot interactively →