Across TCGA patient cohorts, POTEC RNA expression is significantly associated with the go_rna of many other GO terms, with 6,512 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POTEC-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Protein polymerization, and Sister chromatid segregation. Each is linked with POTEC in more than 13 cancer types. Because this analysis shows association rather than direction, both POTEC-to-partner and partner-to-POTEC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEC→partner) and Y-score (partner→POTEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.071	+0.077	<.001	<.001	3	14
ESCA	Protein polymerization →	+0.067	+0.073	<.001	.001	3	13
STAD	Sister chromatid segregation →	+0.078	+0.067	<.001	<.001	3	13
ESCA	Cell cycle checkpoint signaling →	+0.082	+0.084	<.001	.005	2	14
STAD	Regulation of microtubule-based process →	+0.052	+0.071	<.001	<.001	3	13
STAD	Signal transduction in response to DNA damage →	+0.070	+0.058	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,512 associations by consensus.

Exploration

POTEC survival (RNA) · tumor vs normal (RNA) · all POTEC data types