Across TCGA pan-cancer cohorts, POTEA Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated POTEA data layer compared with 11 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher POTEA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POTEA expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, UCEC, and TGCT are the cancer types where POTEA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.650	0.877	.001	17	view →
UCEC	DFS	Median	All	1.000	0.634	.027	8	view →
TGCT	DFS	Median	All	0.002	0.837	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: POTEA tumor-vs-normal RNA expression · all POTEA data types