POR

Across TCGA pan-cancer cohorts, POR mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated POR data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher POR mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated POR expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where POR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.637	1.000	.003	17	view →
HNSC	DFS	Median	All	0.993	0.915	.011	10	view →
PDAC	OS	Tertile	IV	0.425	0.962	.024	5	view →
UCEC	DFS	Median	III,IV	0.889	0.310	.044	4	view →
LUAD	OS	Median	All	0.783	0.969	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

POR–CCRCC (OS)

Open the CCRCC breakdown →