POR

Across TCGA cell cohorts, POR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,811 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible POR-associated GO terms across cancer lineages are Organohalogen metabolic process, Fatty acid catabolic process, and Vacuolar acidification. Each is linked with POR in more than 14 cancer types. Because this analysis shows association rather than direction, both POR-to-partner and partner-to-POR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organohalogen metabolic process grouped by POR-low versus POR-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POR→partner) and Y-score (partner→POR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Organohalogen metabolic process →	+0.253	+1.250	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.074	+0.882	.002	<.001	3	11
OVARY	Vacuolar acidification →	+0.115	+1.080	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.061	+0.873	.006	<.001	3	10
LUNG_SCLC	Fatty acid oxidation →	+0.080	+0.670	.006	.008	3	10
SKIN	Nitric oxide biosynthetic process →	+0.118	+0.725	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,811 associations by consensus.

Organohalogen metabolic process by POR expression — KIDNEY

Explore this box plot interactively →