POPDC3

Across TCGA patient cohorts, POPDC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POPDC3-associated proteins across cancer lineages are BAG2, RAB3D, and NUMBL_S263. Each is linked with POPDC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both POPDC3-to-partner and partner-to-POPDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POPDC3 versus BAG2 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POPDC3→partner) and Y-score (partner→POPDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BAG2 →	+0.516	+0.909	.001	.002	3	5
LSCC	RAB3D →	-0.494	-1.179	.001	<.001	3	4
UCEC	NUMBL_S263 →	+0.530	+0.726	<.001	.001	3	4
UCEC	PRUNE2 →	+0.625	+0.615	<.001	.007	3	3
GBM	TSC1 →	+0.215	+0.797	.001	.005	3	3
UCEC	CDC42BPA →	+0.261	+0.682	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,977 associations by consensus.

POPDC3 vs BAG2 — HNSC

Explore this scatter interactively →