POPDC3

Across TCGA cell cohorts, POPDC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,310 significant associations in total. BONE shows the largest number of these associations.

The most reproducible POPDC3-associated GO terms across cancer lineages are Protein folding, Potassium ion transport, and Potassium ion transmembrane transport. Each is linked with POPDC3 in more than 10 cancer types. Because this analysis shows association rather than direction, both POPDC3-to-partner and partner-to-POPDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by POPDC3-low versus POPDC3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POPDC3→partner) and Y-score (partner→POPDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein folding →	+0.071	+2.226	<.001	<.001	3	11
PANCREAS	Potassium ion transport →	-0.050	-1.807	.001	<.001	3	9
PANCREAS	Potassium ion transmembrane transport →	-0.054	-1.817	<.001	<.001	3	9
BREAST	Membrane bending →	-0.164	-2.108	<.001	<.001	3	9
OESOPHAGUS	DNA-templated transcription initiation →	+0.075	+2.816	<.001	<.001	3	9
SOFT_TISSUE	Protein localization to nuclear envelope →	+0.083	+2.483	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,310 associations by consensus.

Protein folding by POPDC3 expression — OESOPHAGUS

Explore this box plot interactively →