POPDC2

Across TCGA patient cohorts, POPDC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,440 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible POPDC2-associated proteins across cancer lineages are MYLK, PRKG1, and KANK2. Each is linked with POPDC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both POPDC2-to-partner and partner-to-POPDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POPDC2 versus MYLK in COAD, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POPDC2→partner) and Y-score (partner→POPDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MYLK →	+0.858	+0.900	<.001	<.001	3	9
UCEC	PRKG1 →	+0.740	+0.474	.001	.002	3	9
BRCA	KANK2 →	+0.611	+0.551	<.001	<.001	3	9
OV	SEPTIN4 →	+0.585	+0.595	<.001	<.001	3	8
UCEC	TNS1 →	+0.663	+0.465	.002	.001	3	8
COAD	TPM2 →	+1.149	+0.976	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,440 associations by consensus.

POPDC2 vs MYLK — COAD

Explore this scatter interactively →