POPDC2

Across TCGA patient cohorts, POPDC2 protein abundance is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. COAD shows the largest number of these associations.

The most reproducible POPDC2-associated genes across cancer lineages are TPTEP1, HMOX1, and DOK5. Each is linked with POPDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POPDC2-to-partner and partner-to-POPDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POPDC2 versus TPTEP1 in COAD, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POPDC2→partner) and Y-score (partner→POPDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TPTEP1 →	+0.448	+0.481	.001	<.001	3	1
COAD	HMOX1 →	+1.004	+0.398	.005	.008	3	1
COAD	DOK5 →	+0.622	+0.401	.004	.007	3	1
COAD	GATA1 →	+0.472	+0.481	.001	<.001	3	1
COAD	LILRA1 →	+0.631	+0.401	.006	.007	3	1
COAD	SYDE1 →	+0.932	+0.481	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

POPDC2 vs TPTEP1 — COAD

Explore this scatter interactively →