POPDC2

Across TCGA cell cohorts, POPDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,867 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POPDC2-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Macroautophagy, and Negative regulation of myoblast fusion. Each is linked with POPDC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both POPDC2-to-partner and partner-to-POPDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic translation grouped by POPDC2-low versus POPDC2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POPDC2→partner) and Y-score (partner→POPDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of cytoplasmic translation →	+0.122	+0.784	<.001	<.001	3	11
SOFT_TISSUE	Macroautophagy →	+0.045	+0.333	<.001	.001	2	11
OVARY	Negative regulation of myoblast fusion →	+0.123	+0.532	<.001	<.001	3	10
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.116	+0.532	<.001	<.001	3	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.117	+0.518	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of proteasomal protein catabolic process →	+0.056	+0.842	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,867 associations by consensus.

Positive regulation of cytoplasmic translation by POPDC2 expression — LUNG_SCLC

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