POP5

Across TCGA pan-cancer cohorts, POP5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated POP5 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher POP5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated POP5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where POP5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.439	1.000	.010	14	view →
CCRCC	DFS	Quartile	III,IV	0.312	0.772	.008	8	view →
LSCC	DFS	Quartile	All	0.883	0.592	.027	7	view →
PDAC	OS	Median	II,III,IV	0.635	0.374	.039	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

POP5–LUAD (DFS)

Open the LUAD breakdown →