POP5

Across TCGA patient cohorts, POP5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,416 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POP5-associated genes across cancer lineages are PLN, C1QTNF9, and TMEM198. Each is linked with POP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both POP5-to-partner and partner-to-POP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POP5 versus PLN in COAD, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POP5→partner) and Y-score (partner→POP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLN →	-2.000	-0.442	.003	<.001	3	3
BRCA	C1QTNF9 →	-0.231	-0.305	.002	.002	3	3
BRCA	TMEM198 →	+0.761	+0.377	.001	.002	2	3
OV	SMC2-AS1 →	+0.169	+0.222	.005	.003	3	2
CCRCC	SLC16A6 →	+1.156	+0.339	<.001	.001	3	2
COAD	IGLL1 →	-0.213	-0.403	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,416 associations by consensus.

POP5 vs PLN — COAD

Explore this scatter interactively →