POP5

Across TCGA cell cohorts, POP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,252 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POP5-associated GO terms across cancer lineages are Double-strand break repair, Regulation of translational fidelity, and DNA replication initiation. Each is linked with POP5 in more than 11 cancer types. Because this analysis shows association rather than direction, both POP5-to-partner and partner-to-POP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by POP5-low versus POP5-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POP5→partner) and Y-score (partner→POP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Double-strand break repair →	+0.051	+1.037	<.001	<.001	3	12
SKIN	Regulation of translational fidelity →	+0.091	+0.446	.001	.008	3	11
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.144	+0.776	.006	.005	2	11
BREAST	Epidermis development →	-0.166	-0.565	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Interstrand cross-link repair →	+0.084	+0.898	.004	.001	3	10
BLOOD_Myeloma	tRNA processing →	+0.059	+1.103	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,252 associations by consensus.

Double-strand break repair by POP5 expression — BLOOD_Lymphoma

Explore this box plot interactively →