POP1

Across TCGA patient cohorts, POP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,392 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POP1-associated proteins across cancer lineages are YTHDF3, RIF1_S782, and RRM2. Each is linked with POP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both POP1-to-partner and partner-to-POP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POP1 versus YTHDF3 in LUAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POP1→partner) and Y-score (partner→POP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	YTHDF3 →	+0.261	+0.353	<.001	.002	3	7
BRCA	RIF1_S782 →	+0.878	+0.749	<.001	<.001	3	7
UCEC	RRM2 →	+0.785	+0.692	<.001	<.001	3	7
BRCA	MCM5 →	+0.647	+0.469	<.001	<.001	3	7
BRCA	PRRC2C →	+0.195	+0.435	<.001	<.001	3	6
LUAD	TLN1_S2040 →	-0.665	-0.499	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,392 associations by consensus.

POP1 vs YTHDF3 — LUAD

Explore this scatter interactively →