POP1

Across TCGA patient cohorts, POP1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,689 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POP1-associated genes across cancer lineages are ENY2, DCAF13, and NUDCD1. Each is linked with POP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both POP1-to-partner and partner-to-POP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POP1 versus ENY2 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POP1→partner) and Y-score (partner→POP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ENY2 →	+0.662	+0.398	<.001	<.001	3	8
OV	DCAF13 →	+0.857	+0.365	<.001	<.001	3	8
OV	NUDCD1 →	+0.801	+0.291	<.001	<.001	3	7
BRCA	MTERF3 →	+0.828	+0.392	<.001	<.001	3	7
HNSC	PABPC1 →	+1.025	+0.239	<.001	<.001	3	7
GBM	GINS1 →	+0.962	+0.226	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,689 associations by consensus.

POP1 vs ENY2 — BRCA

Explore this scatter interactively →