POMZP3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POMZP3 mutation is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POMZP3-associated genes across cancer lineages are RNA5SP419, RNA5SP422, and RNA5SP416. Each is linked with POMZP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POMZP3-to-partner and partner-to-POMZP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by POMZP3-low versus POMZP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMZP3→partner) and Y-score (partner→POMZP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP419 →+0.984+2.755<.001.00932
UCECRNA5SP422 →+1.091+2.993<.001.00332
UCECRNA5SP416 →+0.709+2.902<.001.00632
UCECRNA5SP421 →+0.891+2.925<.001.00332
UCECRNA5SP423 →+0.919+3.039.001.00232
UCECRNA5SP415 →+0.805+3.167<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

RNA5SP419 by POMZP3 expression — UCEC

Box plot of RNA5SP419 in POMZP3-low vs POMZP3-high samples in UCEC.

Explore this box plot interactively →

Exploration