POMZP3

Across TCGA cell cohorts, POMZP3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POMZP3-associated genes across cancer lineages are GSTA3, EDDM3B, and CNGA2. Each is linked with POMZP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POMZP3-to-partner and partner-to-POMZP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSTA3 grouped by POMZP3-low versus POMZP3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMZP3→partner) and Y-score (partner→POMZP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSTA3 →	+0.132	+4.684	<.001	.002	3	2
BLOOD_Leukemia	EDDM3B →	+0.014	+4.539	<.001	.007	3	1
LARGE_INTESTINE	CNGA2 →	+0.011	+4.930	<.001	.001	3	1
LARGE_INTESTINE	MAGEE2 →	+0.031	+4.684	<.001	.002	3	1
LARGE_INTESTINE	DAZL →	+0.034	+4.467	.007	.004	3	1
BREAST	VCY1B →	+1.590	+4.421	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GSTA3 by POMZP3 expression — LARGE_INTESTINE

Explore this box plot interactively →