POMP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POMP protein abundance is significantly associated with the RNA expression of many other genes, with 8,025 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POMP-associated genes across cancer lineages are TIMM9, SNW1, and DAD1. Each is linked with POMP in more than 4 cancer types. Because this analysis shows association rather than direction, both POMP-to-partner and partner-to-POMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POMP versus TIMM9 in COAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMP→partner) and Y-score (partner→POMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTIMM9 →+0.433+0.429<.001.00334
HNSCSNW1 →+0.421+0.188.007.00334
UCECDAD1 →+0.688+0.328.002.00234
HNSCRAN →+1.128+0.456.002<.00134
HNSCCCT6A →+0.685+0.315<.001<.00134
UCECPSMG3 →+0.927+0.280<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,025 associations by consensus.

POMP vs TIMM9 — COAD

Per-sample scatter of POMP vs TIMM9 in COAD (Pearson r = 0.34).

Explore this scatter interactively →

Exploration