POMP

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POMP mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POMP-associated genes across cancer lineages are lymphatic Endothelial cells. Each is linked with POMP in more than 1 cancer types. Because this analysis shows association rather than direction, both POMP-to-partner and partner-to-POMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by POMP-low versus POMP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMP→partner) and Y-score (partner→POMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEClymphatic Endothelial cells →-0.028-3.116.030.02011
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

lymphatic Endothelial cells by POMP expression — UCEC

Box plot of lymphatic Endothelial cells in POMP-low vs POMP-high samples in UCEC.

Explore this box plot interactively →

Exploration