Across TCGA pan-cancer cohorts, POMK Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated POMK data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher POMK Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POMK expression acts as an unfavorable survival marker.

BRCA and SKCM are the cancer types where POMK Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.103	0.578	<.001	24	view →
SKCM	OS	Median	All	0.348	0.784	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: POMK tumor-vs-normal RNA expression · all POMK data types