POMGNT2

Across TCGA cell cohorts, POMGNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,193 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible POMGNT2-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Regulation of smoothened signaling pathway, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with POMGNT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both POMGNT2-to-partner and partner-to-POMGNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by POMGNT2-low versus POMGNT2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POMGNT2→partner) and Y-score (partner→POMGNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of pinocytosis →	+0.116	+1.180	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.044	+0.797	.005	.009	3	11
LARGE_INTESTINE	Microtubule cytoskeleton organization involved in mitosis →	+0.085	+1.105	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleosome disassembly →	+0.142	+1.183	<.001	<.001	3	10
BREAST	Nucleosome organization →	+0.102	+1.085	<.001	<.001	3	10
KIDNEY	Establishment of mitotic spindle localization →	+0.106	+1.005	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,193 associations by consensus.

Positive regulation of pinocytosis by POMGNT2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →