POMGNT2

Across TCGA cell cohorts, POMGNT2 mutation is significantly associated with the RNA expression of many other genes, with 417 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POMGNT2-associated genes across cancer lineages are SLC30A9, ACTR6, and OC90. Each is linked with POMGNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POMGNT2-to-partner and partner-to-POMGNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC30A9 grouped by POMGNT2-low versus POMGNT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMGNT2→partner) and Y-score (partner→POMGNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC30A9 →	+0.631	+3.502	<.001	.001	3	2
LARGE_INTESTINE	ACTR6 →	+0.670	+3.588	<.001	<.001	3	2
BLOOD_Leukemia	OC90 →	+0.006	+3.464	<.001	.003	3	1
BLOOD_Lymphoma	DEFB124 →	+0.141	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	SCGB1C1 →	+0.146	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	OR52K1 →	+0.022	+5.169	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 417 associations by consensus.

SLC30A9 by POMGNT2 expression — LARGE_INTESTINE

Explore this box plot interactively →