POMGNT1

Across TCGA patient cohorts, POMGNT1 mutation is significantly associated with the RNA expression of many other genes, with 1,611 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POMGNT1-associated genes across cancer lineages are COX6CP17, GAGE2E, and IGHVII-15-1. Each is linked with POMGNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both POMGNT1-to-partner and partner-to-POMGNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6CP17 grouped by POMGNT1-low versus POMGNT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMGNT1→partner) and Y-score (partner→POMGNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	COX6CP17 →	+0.139	+3.699	<.001	.003	3	3
BRCA	GAGE2E →	+0.258	+5.649	<.001	.001	3	2
BRCA	IGHVII-15-1 →	+0.124	+5.201	<.001	.002	3	2
BRCA	MIR4518 →	+0.343	+3.812	.009	.007	3	2
LUAD	RNU1-62P →	+0.218	+6.315	<.001	.001	3	2
UCEC	CENPM →	+0.490	+2.137	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,611 associations by consensus.

COX6CP17 by POMGNT1 expression — SKCM

Explore this box plot interactively →