POMGNT1

Across TCGA cell cohorts, POMGNT1 mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POMGNT1-associated genes across cancer lineages are KDELR3, RBFA, and PARD6A. Each is linked with POMGNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both POMGNT1-to-partner and partner-to-POMGNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KDELR3 grouped by POMGNT1-low versus POMGNT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMGNT1→partner) and Y-score (partner→POMGNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KDELR3 →	+1.175	+3.212	.001	.006	3	1
LARGE_INTESTINE	RBFA →	+0.693	+3.212	.008	.006	3	1
LARGE_INTESTINE	PARD6A →	+0.963	+3.299	<.001	.004	3	1
LARGE_INTESTINE	SNAPC2 →	+0.685	+3.212	.003	.006	3	1
LARGE_INTESTINE	HFE →	+0.893	+3.212	.003	.006	3	1
LARGE_INTESTINE	HINT3 →	+0.721	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

KDELR3 by POMGNT1 expression — LARGE_INTESTINE

Explore this box plot interactively →