POM121L6P

Across TCGA pan-cancer cohorts, POM121L6P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of POM121L6P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where POM121L6P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POM121L6P is over-expressed in tumor.

KIRC, KICH, and LUAD are the cancer types where POM121L6P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POM121L6P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.020	<.001	7	view →
KICH	All	All	+0.010	.013	3	view →
LUAD	All	All	+0.066	.009	2	view →
PRAD	All	All	+0.032	.005	2	view →
LUSC	All	All	+0.024	.020	2	view →
STAD	All	II,III,IV	+0.092	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

POM121L6P–KIRC

Open the KIRC breakdown →