POM121L2

Across TCGA patient cohorts, POM121L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,861 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POM121L2-associated GO terms across cancer lineages are Mitotic cytokinesis, Ribosome assembly, and Cytoskeleton-dependent cytokinesis. Each is linked with POM121L2 in more than 18 cancer types. Because this analysis shows association rather than direction, both POM121L2-to-partner and partner-to-POM121L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis grouped by POM121L2-low versus POM121L2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121L2→partner) and Y-score (partner→POM121L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitotic cytokinesis →	+0.087	+0.362	<.001	.001	3	18
ESCA	Ribosome assembly →	+0.081	+0.301	.001	.002	3	18
STAD	Cytoskeleton-dependent cytokinesis →	+0.059	+0.123	<.001	<.001	3	18
ESCA	Cytokinesis →	+0.071	+0.255	.001	.002	3	18
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.065	+0.130	<.001	<.001	3	17
STAD	RNA capping →	+0.059	+0.132	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,861 associations by consensus.

Mitotic cytokinesis by POM121L2 expression — ESCA

Explore this box plot interactively →