Across TCGA pan-cancer cohorts, POM121L1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of POM121L1P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where POM121L1P RNA is repressed in tumor relative to normal tissue. In most cancer types POM121L1P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, HNSC, and LUAD are the cancer types where POM121L1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POM121L1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.098	<.001	8	view →
HNSC	All	All	+0.005	.030	4	view →
LUAD	Female	All	+0.010	.007	3	view →
KICH	Male	III,IV	−0.020	.030	2	view →
CHOL	All	All	+0.021	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: POM121L1P RNA expression & survival · all POM121L1P data types