Across TCGA cell cohorts, POM121L12 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POM121L12-associated genes across cancer lineages are OR2L5, DDX53, and CGB1. Each is linked with POM121L12 in more than 1 cancer types. Because this analysis shows association rather than direction, both POM121L12-to-partner and partner-to-POM121L12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121L12→partner) and Y-score (partner→POM121L12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2L5 →	+0.007	+2.887	.002	.009	3	2
LUNG_SCLC	DDX53 →	+1.188	+3.263	<.001	.009	3	2
LUNG_SCLC	CGB1 →	+1.379	+3.528	<.001	.006	3	2
BLOOD_Lymphoma	OR6C2 →	+0.064	+4.169	.002	.002	3	1
BLOOD_Lymphoma	OR7A5 →	+0.021	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	SCYGR4 →	+0.018	+4.169	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

Exploration

POM121L12 survival (RNA) · tumor vs normal (RNA) · all POM121L12 data types