Across TCGA patient cohorts, POM121 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POM121-associated proteins across cancer lineages are FOXK1, GTF2I, and RBM12B_S280. Each is linked with POM121 in more than 5 cancer types. Because this analysis shows association rather than direction, both POM121-to-partner and partner-to-POM121 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121→partner) and Y-score (partner→POM121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOXK1 →	+0.388	+0.687	<.001	<.001	3	6
GBM	GTF2I →	+0.492	+0.541	<.001	<.001	3	6
PDAC	RBM12B_S280 →	+0.954	+0.323	.004	.001	3	5
LSCC	MPRIP_S301 →	-0.733	-0.396	<.001	.004	3	5
HNSC	LRWD1 →	+0.351	+0.778	<.001	<.001	3	5
LSCC	MEPCE →	+0.452	+0.669	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,131 associations by consensus.

Exploration

POM121 survival (RNA) · tumor vs normal (RNA) · all POM121 data types