Across TCGA patient cohorts, POM121 protein abundance is significantly associated with the RNA expression of many other genes, with 3,437 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible POM121-associated genes across cancer lineages are PUM2, RNU4-24P, and CYP4F8. Each is linked with POM121 in more than 3 cancer types. Because this analysis shows association rather than direction, both POM121-to-partner and partner-to-POM121 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121→partner) and Y-score (partner→POM121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PUM2 →	+0.534	+0.273	.008	.002	3	4
OV	RNU4-24P →	+0.459	+0.422	.002	.009	3	2
BRCA	CYP4F8 →	-1.279	-0.277	<.001	.002	3	2
COAD	EEF1B2P6 →	+0.949	+0.609	.003	.002	3	2
COAD	RPL13AP6 →	+0.880	+0.609	.005	.002	3	2
HNSC	RPL5P23 →	+0.820	+0.220	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,437 associations by consensus.

Exploration

POM121 survival (RNA) · tumor vs normal (RNA) · all POM121 data types