Across TCGA cell cohorts, POM121 mutation is significantly associated with the RNA expression of many other genes, with 750 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POM121-associated genes across cancer lineages are OR51M1, NCR1, and SSMEM1. Each is linked with POM121 in more than 1 cancer types. Because this analysis shows association rather than direction, both POM121-to-partner and partner-to-POM121 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121→partner) and Y-score (partner→POM121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR51M1 →	+0.109	+2.643	.003	.002	3	2
BREAST	NCR1 →	+0.214	+4.199	<.001	.007	3	2
BLOOD_Leukemia	SSMEM1 →	+0.078	+3.669	<.001	.002	3	2
LUNG_SCLC	TRIM48 →	+0.032	+3.684	.007	.001	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
SKIN	PRY →	+0.693	+3.693	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 750 associations by consensus.

Exploration

POM121 survival (RNA) · tumor vs normal (RNA) · all POM121 data types