POLR3KP2

Across TCGA pan-cancer cohorts, POLR3KP2 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated POLR3KP2 data layer.

The strongest signal is observed in thymoma (THYM), where higher POLR3KP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated POLR3KP2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

THYM, PAAD, and KIRC are the cancer types where POLR3KP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Tertile	II,III,IV	0.628	0.950	<.001	54	view →
PAAD	OS	Tertile	All	0.951	0.574	<.001	48	view →
KIRC	DFS	Tertile	III,IV	0.285	0.523	.007	39	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	24	view →
SKCM	DFS	Tertile	III,IV	0.165	0.496	.026	18	view →
TGCT	DFS	Tertile	III,IV	0.017	0.923	.021	18	view →
OV	DFS	Tertile	IV	0.685	0.432	.046	18	view →
LAML	DFS	Median	All	0.672	0.492	.011	18	view →
LIHC	DFS	Tertile	II,III,IV	0.107	0.431	.006	18	view →
THCA	DFS	Tertile	II,III,IV	0.776	0.927	.046	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

POLR3KP2–THYM (DFS)

Open the THYM breakdown →