POLR3KP1

Across TCGA patient cohorts, POLR3KP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,285 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR3KP1-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Telomere maintenance, and Obsolete cellular response to extracellular stimulus. Each is linked with POLR3KP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both POLR3KP1-to-partner and partner-to-POLR3KP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by POLR3KP1-low versus POLR3KP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3KP1→partner) and Y-score (partner→POLR3KP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein ubiquitination →	+0.110	+0.039	<.001	<.001	3	8
STAD	Telomere maintenance →	+0.122	+0.030	<.001	.001	3	7
STAD	Obsolete cellular response to extracellular stimulus →	+0.090	+0.056	<.001	<.001	3	7
STAD	Regulation of binding →	+0.101	+0.036	<.001	<.001	3	7
STAD	Cellular response to radiation →	+0.100	+0.044	<.001	.001	3	7
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.121	+0.052	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,285 associations by consensus.

Regulation of protein ubiquitination by POLR3KP1 expression — STAD

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