POLR3K

Across TCGA patient cohorts, POLR3K RNA expression is significantly associated with the protein abundance of many other proteins, with 16,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR3K-associated proteins across cancer lineages are DCTPP1, GSPT1, and NFATC2IP. Each is linked with POLR3K in more than 7 cancer types. Because this analysis shows association rather than direction, both POLR3K-to-partner and partner-to-POLR3K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3K versus DCTPP1 in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3K→partner) and Y-score (partner→POLR3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DCTPP1 →	+0.537	+0.545	<.001	<.001	3	8
OV	GSPT1 →	+0.236	+0.578	.001	<.001	3	7
PDAC	NFATC2IP →	+0.326	+0.317	.001	.002	2	8
BRCA	NFATC2IP_S204 →	+0.473	+0.566	<.001	<.001	3	7
BRCA	ATXN2L →	+0.264	+0.694	<.001	<.001	3	7
BRCA	PARN →	+0.317	+0.721	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,635 associations by consensus.

POLR3K vs DCTPP1 — BRCA

Explore this scatter interactively →