Across TCGA pan-cancer cohorts, POLR2KP2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of POLR2KP2’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where POLR2KP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POLR2KP2 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

STAD and LUSC are the cancer types where POLR2KP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POLR2KP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.060	.040	2	view →
LUSC	Female	All	−0.125	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: POLR2KP2 RNA expression & survival · all POLR2KP2 data types