POLR2J4

Across TCGA patient cohorts, POLR2J4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,962 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POLR2J4-associated proteins across cancer lineages are MEPCE, SART3, and KBTBD2. Each is linked with POLR2J4 in more than 4 cancer types. Because this analysis shows association rather than direction, both POLR2J4-to-partner and partner-to-POLR2J4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2J4 versus MEPCE in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J4→partner) and Y-score (partner→POLR2J4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEPCE →	+0.295	+0.355	<.001	<.001	3	5
GBM	SART3 →	+0.285	+0.390	<.001	.001	3	5
GBM	KBTBD2 →	+0.252	+0.417	.001	<.001	3	5
GBM	THOC1 →	+0.309	+0.436	<.001	<.001	3	5
HNSC	PURB →	+0.316	+0.545	<.001	<.001	3	5
LSCC	SPCS3 →	-0.540	-0.456	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,962 associations by consensus.

POLR2J4 vs MEPCE — GBM

Explore this scatter interactively →