POLR2J3

Across TCGA patient cohorts, POLR2J3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,112 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible POLR2J3-associated GO terms across cancer lineages are Peptidyl-lysine modification, DNA biosynthetic process, and Positive regulation of DNA repair. Each is linked with POLR2J3 in more than 25 cancer types. Because this analysis shows association rather than direction, both POLR2J3-to-partner and partner-to-POLR2J3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by POLR2J3-low versus POLR2J3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J3→partner) and Y-score (partner→POLR2J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Peptidyl-lysine modification →	+0.055	+0.652	<.001	<.001	3	26
STAD	DNA biosynthetic process →	+0.047	+0.413	<.001	<.001	3	25
SCLC	Positive regulation of DNA repair →	+0.065	+0.869	<.001	<.001	3	25
SCLC	Obsolete histone modification →	+0.071	+0.535	<.001	<.001	3	25
SCLC	Positive regulation of chromosome organization →	+0.077	+0.716	<.001	<.001	3	24
SCLC	Regulation of double-strand break repair →	+0.047	+0.624	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,112 associations by consensus.

Peptidyl-lysine modification by POLR2J3 expression — SCLC

Explore this box plot interactively →