POLR2J3

Across TCGA cell cohorts, POLR2J3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,498 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible POLR2J3-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of pattern recognition receptor signaling pathway, and snoRNA guided rRNA pseudouridine synthesis. Each is linked with POLR2J3 in more than 8 cancer types. Because this analysis shows association rather than direction, both POLR2J3-to-partner and partner-to-POLR2J3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by POLR2J3-low versus POLR2J3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J3→partner) and Y-score (partner→POLR2J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.145	+0.999	<.001	.002	3	9
BREAST	Regulation of pattern recognition receptor signaling pathway →	+0.048	+0.896	.003	.003	3	7
SKIN	snoRNA guided rRNA pseudouridine synthesis →	-0.098	-0.865	<.001	.003	3	7
CNS	Establishment of meiotic sister chromatid cohesion →	-0.120	-0.702	.007	.003	3	7
PANCREAS	Positive regulation of dendritic cell differentiation →	-0.170	-1.039	<.001	<.001	3	6
LUNG_NSCLC_LUSC	Nuclear matrix anchoring at nuclear membrane →	+0.228	+1.237	.006	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,498 associations by consensus.

Pre-mRNA catabolic process by POLR2J3 expression — LARGE_INTESTINE

Explore this box plot interactively →