POLR2I

Across TCGA patient cohorts, POLR2I mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible POLR2I-associated genes across cancer lineages are Monocytes. Each is linked with POLR2I in more than 1 cancer types. Because this analysis shows association rather than direction, both POLR2I-to-partner and partner-to-POLR2I results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by POLR2I-low versus POLR2I-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2I→partner) and Y-score (partner→POLR2I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.024	+6.810	<.001	.017	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Monocytes by POLR2I expression — SKCM

Explore this box plot interactively →